The effect of deferasirox on endocrine complications in children with thalassemia.

Endocrine system dysfunctions are the significant complications of excessive iron overload in beta thalassemia patients. The aim of this study was to evaluate the long-term effect of chelation with deferasirox on endocrine complications.

The study group consisted of children with beta thalassemia who had been evaluated for the growth and pubertal development, bone metabolism, thyroid/parathyroid functions, glucose metabolism dysfunctions in the department of pediatric hematology of Ankara Dışkapı Child Health and Diseases Hematology Oncology Training And Research Hospital between 2009-2011 and reevaluated after deferasirox chelation therapy in 2018. Thirty-one transfusion dependent beta-thalassemia patients were enrolled for the study. 

Human Cerberus (CER) ELISA Kit

DLR-CER-Hu-48T 48T
EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human Cerberus (CER) in samples from serum, plasma, tissue homogenates or other biological fluids.

Human Cerberus (CER) ELISA Kit

DLR-CER-Hu-96T 96T
EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human Cerberus (CER) in samples from serum, plasma, tissue homogenates or other biological fluids.

Mouse Cerberus (CER) ELISA Kit

DLR-CER-Mu-48T 48T
EUR 527
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cerberus (CER) in samples from serum, plasma or other biological fluids.

Mouse Cerberus (CER) ELISA Kit

DLR-CER-Mu-96T 96T
EUR 688
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Cerberus (CER) in samples from serum, plasma or other biological fluids.

Human Cerberus (CER) ELISA Kit

RDR-CER-Hu-48Tests 48 Tests
EUR 544

Human Cerberus (CER) ELISA Kit

RDR-CER-Hu-96Tests 96 Tests
EUR 756

Mouse Cerberus (CER) ELISA Kit

RDR-CER-Mu-48Tests 48 Tests
EUR 557

Mouse Cerberus (CER) ELISA Kit

RDR-CER-Mu-96Tests 96 Tests
EUR 774

1730 8 SNAP-SEAL 8 OZ

1730-8 100/pk
EUR 74
Description: Disposable Plastic; Plastic Containers

Individual Reaction Mix 8

G065-8 200 reactions
EUR 167

Human IL-8 Recombinant Protein

R00423-8 5ug/vial
EUR 259
Description: Interleukin-8 (IL-8), also known as CXCL8, is an ELR-positive CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. Human IL-8 Recombinant Protein is purified interleukin-8 produced in yeast.

8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

DLR-8-OHdG-Ge-48T 48T
EUR 469
Description: A competitive inhibition quantitative ELISA assay kit for detection of 8-Hydroxydeoxyguanosine (8-OHdG) in samples from serum, plasma or other biological fluids.

8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

DLR-8-OHdG-Ge-96T 96T
EUR 608
Description: A competitive inhibition quantitative ELISA assay kit for detection of 8-Hydroxydeoxyguanosine (8-OHdG) in samples from serum, plasma or other biological fluids.

0.5-10UL 8-CHANNEL, DIGITAL PIPETTOR

AP-8-10 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

20-200UL 8-CHANNEL, DIGITAL PIPETTOR

AP-8-200 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

50-300UL 8-CHANNEL, DIGITAL PIPETTOR

AP-8-300 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

5-50UL 8-CHANNEL, DIGITAL PIPETTOR

AP-8-50 1/pk
EUR 425
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Cerberus (CER) Antibody

20-abx175778
  • EUR 1205.00
  • EUR 578.00
  • 1 mg
  • 200 ug

Cerberus (CER) Antibody

20-abx175779
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug

Cerberus (CER) Antibody

20-abx175780
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug

Cerberus (CER) Antibody

20-abx171669
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RD-8-OHdG-Ge-48Tests 48 Tests
EUR 467

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RD-8-OHdG-Ge-96Tests 96 Tests
EUR 646

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RDR-8-OHdG-Ge-48Tests 48 Tests
EUR 488

General 8-Hydroxydeoxyguanosine (8-OHdG) ELISA Kit

RDR-8-OHdG-Ge-96Tests 96 Tests
EUR 676

pAAV-DJ/8 Vector

VPK-420-DJ-8 10 µg
EUR 647
Description: The pAAV-DJ/8 vector contains the rep and cap genes required to generated recombinant AAV of serotype DJ/8. Co-transfect with other packaging plasmids and an expression vector into 293 cells for AAV-DJ/8 packaging.

Sheep CER ELISA Kit

ESC0097 96Tests
EUR 521

Mouse CER ELISA Kit

EMC0097 96Tests
EUR 521

Anserini CER ELISA Kit

EAC0097 96Tests
EUR 521

Rabbit CER ELISA Kit

ERTC0097 96Tests
EUR 521

Monkey CER ELISA Kit

EMKC0097 96Tests
EUR 521

Porcine CER ELISA Kit

EPC0097 96Tests
EUR 521

Rat CER ELISA Kit

ERC0097 96Tests
EUR 521

Human CER ELISA Kit

EHC0097 96Tests
EUR 521

Canine CER ELISA Kit

ECC0097 96Tests
EUR 521

Chicken CER ELISA Kit

ECKC0097 96Tests
EUR 521

Goat CER ELISA Kit

EGTC0097 96Tests
EUR 521

Bovine CER ELISA Kit

EBC0097 96Tests
EUR 521

Human Cerebellin (CER) Antibody

33279-05111 150 ug
EUR 261

Human Cerberus (CER) Protein

20-abx652843
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Cerberus (CER) Protein

20-abx652844
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Cerberus (CER) Protein

20-abx652845
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

PSA (Prostate-specific antigen) ELISA test

8 96T/Box Ask for price
Description: ELISA based test for quantitative detection of PSA (Prostate-specific antigen)

AAV-DJ/8 Helper Free Packaging System

VPK-400-DJ-8 1 kit
EUR 972
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1).

AAV-DJ/8 Helper Free Expression System

VPK-410-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

scAAV-DJ/8 Helper Free Expression System

VPK-430-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Promoterless Expression System

VPK-411-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

Human Cerberus (CER)CLIA Kit

SCC125Hu-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Cerberus (CER) in serum, plasma and other biological fluids.

Human Cerberus (CER)CLIA Kit

SCC125Hu-1x48wellstestplate 1x48-wells test plate
EUR 552.76
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Cerberus (CER) in serum, plasma and other biological fluids.

Human Cerberus (CER)CLIA Kit

SCC125Hu-1x96wellstestplate 1x96-wells test plate
EUR 746.8
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Cerberus (CER) in serum, plasma and other biological fluids.

Human Cerberus (CER)CLIA Kit

SCC125Hu-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Cerberus (CER) in serum, plasma and other biological fluids.

Human Cerberus (CER) CLIA Kit

4-SCC125Hu
  • EUR 5698.00
  • EUR 3061.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Cerberus (CER)Serum, plasma and other biological fluids

Mouse Cerberus (CER)CLIA Kit

SCC125Mu-10x96wellstestplate 10x96-wells test plate
EUR 5804.88
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Cerberus (CER) in serum, plasma and other biological fluids.

Mouse Cerberus (CER)CLIA Kit

SCC125Mu-1x48wellstestplate 1x48-wells test plate
EUR 565.7
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Cerberus (CER) in serum, plasma and other biological fluids.

Mouse Cerberus (CER)CLIA Kit

SCC125Mu-1x96wellstestplate 1x96-wells test plate
EUR 765.28
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Cerberus (CER) in serum, plasma and other biological fluids.

Mouse Cerberus (CER)CLIA Kit

SCC125Mu-5x96wellstestplate 5x96-wells test plate
EUR 3143.76
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Cerberus (CER) in serum, plasma and other biological fluids.

Mouse Cerberus (CER) CLIA Kit

4-SCC125Mu
  • EUR 5855.00
  • EUR 3144.00
  • EUR 766.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Mouse Cerberus (CER)Serum, plasma and other biological fluids

Human Cerberus (CER) ELISA Kit

SEC125Hu-10x96wellstestplate 10x96-wells test plate
EUR 4731.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cerberus (CER) in serum, plasma, tissue homogenates and other biological fluids.

Human Cerberus (CER) ELISA Kit

SEC125Hu-1x48wellstestplate 1x48-wells test plate
EUR 477.3
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cerberus (CER) in serum, plasma, tissue homogenates and other biological fluids.

Human Cerberus (CER) ELISA Kit

SEC125Hu-1x96wellstestplate 1x96-wells test plate
EUR 639
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cerberus (CER) in serum, plasma, tissue homogenates and other biological fluids.

Human Cerberus (CER) ELISA Kit

SEC125Hu-5x96wellstestplate 5x96-wells test plate
EUR 2575.5
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Cerberus (CER) in serum, plasma, tissue homogenates and other biological fluids.

Human Cerberus (CER) ELISA Kit

4-SEC125Hu
  • EUR 4782.00
  • EUR 2526.00
  • EUR 640.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Cerberus (CER) in samples from Serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Cerberus (CER) ELISA Kit

SEC125Mu-10x96wellstestplate 10x96-wells test plate
EUR 4862.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cerberus (CER) in serum, plasma and other biological fluids.

Mouse Cerberus (CER) ELISA Kit

SEC125Mu-1x48wellstestplate 1x48-wells test plate
EUR 488.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cerberus (CER) in serum, plasma and other biological fluids.

Mouse Cerberus (CER) ELISA Kit

SEC125Mu-1x96wellstestplate 1x96-wells test plate
EUR 654.4
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cerberus (CER) in serum, plasma and other biological fluids.

Mouse Cerberus (CER) ELISA Kit

SEC125Mu-5x96wellstestplate 5x96-wells test plate
EUR 2644.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Cerberus (CER) in serum, plasma and other biological fluids.

Mouse Cerberus (CER) ELISA Kit

4-SEC125Mu
  • EUR 4913.00
  • EUR 2595.00
  • EUR 655.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Cerberus (CER) in samples from Serum, plasma and other biological fluids. with no significant corss-reactivity with analogues from other species.

Anserini CP/CER ELISA Kit

EAC0813 96Tests
EUR 521

Rat CP/CER ELISA Kit

ERC0813 96Tests
EUR 521

Rabbit CP/CER ELISA Kit

ERTC0813 96Tests
EUR 521

Mouse CP/CER ELISA Kit

EMC0813 96Tests
EUR 521

Porcine CP/CER ELISA Kit

EPC0813 96Tests
EUR 521

Human CP/CER ELISA Kit

EHC0813 96Tests
EUR 521

Canine CP/CER ELISA Kit

ECC0813 96Tests
EUR 521

Guinea Pig CER ELISA Kit

EGC0097 96Tests
EUR 521

Goat CP/CER ELISA Kit

EGTC0813 96Tests
EUR 521

Bovine CP/CER ELISA Kit

EBC0813 96Tests
EUR 521

Human Cerberus (CER)ELISA Kit

201-12-2888 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Cerberus (CER) CLIA Kit

20-abx190288
  • EUR 7911.00
  • EUR 4215.00
  • EUR 973.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Cerberus (CER) CLIA Kit

20-abx190562
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Cerberus (CER) ELISA Kit

20-abx151035
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Cerberus (CER) ELISA Kit

20-abx153809
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

CER ELISA Kit (Human) (OKCD04478)

OKCD04478 96 Wells
EUR 831
Description: Description of target: This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 13.3 pg/mL

CER ELISA Kit (Mouse) (OKCD04479)

OKCD04479 96 Wells
EUR 857
Description: Description of target: ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 11.7 pg/mL

Human Cerberus(CER)ELISA Kit

QY-E05054 96T
EUR 413

General 8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a) ELISA Kit

RD-8-epi-PGF2a-Ge-48Tests 48 Tests
EUR 467

General 8-Epi Prostaglandin F2 Alpha (8-epi-PGF2a) ELISA Kit

RD-8-epi-PGF2a-Ge-96Tests 96 Tests
EUR 646

AXYGEN® 8-WELL COMB FOR USE WITH 10 CM GEL BOX, 1.0 MM THICKNESS

HGB10-8-1 1/pk
EUR 59
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.0 MM THICKNESS

HGB15-8-1 1/pk
EUR 69
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-8-15 1/pk
EUR 69
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 7 CM GEL BOX, 0.75 MM THICKNESS

HGB7-8-075 1/pk
EUR 54
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 7 CM GEL BOX, 1.0 MM THICKNESS

HGB7-8-1 1/pk
EUR 54
Description: Lab Equipment; Axygen Branded EQ

AAV-DJ/8 Helper Free Bicistronic Expression System (Puro)

VPK-415-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (Neo)

VPK-416-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (Hygro)

VPK-417-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

AAV-DJ/8 Helper Free Bicistronic Expression System (GFP)

VPK-418-DJ-8 1 kit
EUR 1239
Description: The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.

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